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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2400889Generated: November 1, 2026

1-(4-fluoro-2-(trifluoromethyl)benzyl)-1H-indazole-5-carbaldehyde → HCID 86659652, compound

https://huagongshe.com/reaction/2400889

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(4-fluoro-2-(trifluoromethyl)benzyl)-1H-indazole-5-carbaldehydeHCID 86654587—
ReactantHCID 86659650HCID 86659650—
ProductHCID 86659652HCID 86659652—

Reaction Steps

(5Z)-5-({1-[4-Fluoro-2-(trifluoromethyl)benzyl]-1H-indazol-5-yl}methylidene)-3-[trans-4-hydroxypiperidin-3-yl]-1,3-thiazolidine-2,4-dione was prepared from [4-fluoro-2-(trifluoromethyl)benzyl]-1H-indazol-5-carbaldehyde (from Example 5) and 1,1-dimethylethyl trans-3-(2,4-dioxo-1,3-thiazolidin-3-yl)-4-hydroxy-piperidine-1-carboxylate (from Example 270) following General Procedure F.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08796256B2
Source datasetuspto-grants-2014_08
ORD IDord-cbd2a465645c40ae8dcdde0d47dce5c8
Source noteuspto-grants-2014_08