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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2400898Generated: October 31, 2026

tert-butyl (2R)-2-(hydroxymethyl)piperidine-1-carboxylate → HCID 86659658, compound

https://huagongshe.com/reaction/2400898

Reaction equation

Participants

RoleNameHCIDCharge
Reactanttert-butyl (2R)-2-(hydroxymethyl)piperidine-1-carboxylateHCID 6933953—
ReactantHCID 86659608HCID 86659608—
ProductHCID 86659658HCID 86659658—

Reaction Steps

1,1-Dimethylethyl (2R)-2-[{(5Z)-5-[(1-{[4-chloro-2-(trifluoromethyl)phenyl]-methyl}-1H-indazol-5-yl)methylidene]-2,4-dioxo-1,3-thiazolidin-3-yl]methyl}pyrrolidine-1-carboxylate was prepared from (5Z)-5-({1-[4-chloro-2-(trifluoromethyl)benzyl]-1H-indazol-5-yl}methylidene)-2,4-dioxo-1,3-thiazolidine (from Example 1) and 1,1-dimethylethyl (2R)-2-(hydroxymethyl)piperidine-1-carboxylate following General Procedure J.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08796256B2
Source datasetuspto-grants-2014_08
ORD IDord-ca50955b77074648a18a52de34e88517
Source noteuspto-grants-2014_08