Cyclopropanecarbonyl chloride → HCID 86762579, compound

Participants

Reaction Steps

N-(4-{[(5Z)-5-({1-[2,4-Bis(trifluoromethyl)benzyl]-1H-indazol-5-yl}methylidene)-2,4-dioxo-1,3-thiazolidin-3-yl]methyl}tetrahydro-2H-pyran-4-yl)cyclopropane carboxamide was prepared from (5Z)-3-[(4-aminotetrahydro-2H-pyran-4-yl)methyl]-5-({1-[2,4-bis(trifluoromethyl)benzyl]-1H-indazol-5-yl}methylidene)-1,3-thiazolidine-2,4-dione (Example 310) and cyclopropanecarbonyl chloride following General Procedure R3.

Provenance & Evidence