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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2400937Generated: October 30, 2026

1-(4-chloro-2-(trifluoromethyl)benzyl)-1H-indazole-5-carbaldehyde → HCID 86659684, compound

https://huagongshe.com/reaction/2400937

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(4-chloro-2-(trifluoromethyl)benzyl)-1H-indazole-5-carbaldehydeHCID 86654547—
ReactantHCID 86659650HCID 86659650—
ProductHCID 86659684HCID 86659684—

Reaction Steps

(5Z)-3-{5-[1-(4-chloro-2-trifluoromethylbenzyl)-1H-indazol-5-ylmethylene]-2,4-dioxothiazolidin-3-yl}-4-hydroxypiperidine-1-carboxylic acid tert-butyl ester was prepared from 1,1-dimethylethyl trans-3-(2,4-dioxo-1,3-thiazolidin-3-yl)-4-hydroxypiperidine-1-carboxylate (from Example 270) and [4-chloro-2-(trifluoromethyl)benzyl]-1H-indazol-5-carbaldehyde (from Example 1) following General Procedure F1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08796256B2
Source datasetuspto-grants-2014_08
ORD IDord-e685f4899ce449dd8ee24136f1d1434e
Source noteuspto-grants-2014_08