HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2400940Generated: October 30, 2026
Acetic Anhydride → N-(3-fluoro-2-methylphenyl)acetamide
https://huagongshe.com/reaction/2400940
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | 3-Fluoro-2-methylaniline | HCID 285553 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | N-(3-fluoro-2-methylphenyl)acetamide | HCID 1489284 | — |
Reaction Steps
To the solution of 3-fluoro-2-methylphenylamine (40 mmol) in toluene (50 mL) was added acetic anhydride (47 mmol). The mixture was heated to 100° C. for 1 h, then concentrated to give N-(3-fluoro-2-methylphenyl)acetamide as an off-white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08796256B2 |
|---|
| Source dataset | uspto-grants-2014_08 |
|---|
| ORD ID | ord-df6912b6e5594f2b870f9e0e3def4d16 |
|---|
| Source note | uspto-grants-2014_08 |
|---|
