HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromine → N-(4-Bromo-3-fluoro-2-methylphenyl)acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bromine | HCID 24408 | — |
| Reactant | N-(3-fluoro-2-methylphenyl)acetamide | HCID 1489284 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | N-(4-Bromo-3-fluoro-2-methylphenyl)acetamide | HCID 67123438 | — |
Reaction Steps
To a solution of N-(3-Fluoro-2-methylphenyl)acetamide (39 mmol) in acetic acid (50 mL) was added bromine (40 mmol) in dropwise fashion. After stirring at rt for 2 days, the precipitated product was filtered, washed with water, and dried under high vacuum. N-(4-Bromo-3-fluoro-2-methylphenyl)acetamide was obtained as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08796256B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-821875d27e5f4b619e1cbcb7213e5098 |
| Source note | uspto-grants-2014_08 |