HCID 18929264, compound → 2-Diisopropylphosphinomethyl-2'-methyl-1,1'-binaphthyl

HRID 2401Notes

Reaction equation

HRID 2401 reaction equation
[Br-].[CH:2]([P+:5]1([CH:28]([CH3:30])[CH3:29])[CH2:11][C:10]2[CH:12]=[CH:13][C:14]3[C:19]([C:9]=2[C:8]2[C:20]4[CH:21]=[CH:22][CH:23]=[CH:24][C:25]=4[CH:26]=[CH:27][C:7]=2[CH2:6]1)=[CH:18][CH:17]=[CH:16][CH:15]=3)([CH3:4])[CH3:3].[H-].[Al+3].[Li+].[H-].[H-].[H-]>C1(C)C=CC=CC=1>[CH:28]([P:5]([CH2:6][C:7]1[CH:27]=[CH:26][C:25]2[C:20](=[CH:21][CH:22]=[CH:23][CH:24]=2)[C:8]=1[C:9]1[C:19]2[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=2)[CH:13]=[CH:12][C:10]=1[CH3:11])[CH:2]([CH3:4])[CH3:3])([CH3:29])[CH3:30]

Participants

4

Reactant 2

HCID 18929264HCID 18929264, compoundHCID 21226445Aluminium lithium hydride

Product 1

HCID 196903612-Diisopropylphosphinomethyl-2'-methyl-1,1'-binaphthyl

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

4 g (8.4 mmol) of 4,4-diisopropyl-4,5-dihydro-3H-dinaphtho[2,1-c:1',2'-e]phosphepinium bromide are suspended in 70 ml of absolute toluene under protective gas and reacted with 400 mg (10.5 mmol) of lithium aluminum hydride using a method analogous to Example 5.

Sources & evidence

ORD record
ord-7819582fed694c3f99e1f2746fab150a
Source dataset
uspto-grants-1998_03
Patent number
US05728886

Reaction notes

Loading…