HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Methylamino)benzonitrile → HCID 57444240, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Methylamino)benzonitrile | HCID 10964551 | — |
| Reactant | N-{3-[4-(chloromethyl)phenyl]pyrazin-2-yl}-2-(trifluoromethyl)benzenesulfonamide | HCID 57444250 | — |
| Product | HCID 57444240 | HCID 57444240 | 71% |
Reaction Steps
Following the general method as outlined in Example 1 (Method B), starting from N-{3-[4-(chloromethyl)phenyl]pyrazin-2-yl}-2-(trifluoromethyl)benzene sulfonamide (Intermediate 9), and 4-(N-methylamino)benzonitrile, the title compound was isolated as a yellow solid in 71% yield (94% purity by HPLC).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08796280B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-231564c8854443c8a1a45405c6cd2c14 |
| Source note | uspto-grants-2014_08 |