HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,4-difluoro-N-methylaniline → HCID 11960560, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,4-difluoro-N-methylaniline | HCID 2737023 | — |
| Reactant | 2-chloro-N-{3-[4-(chloromethyl)phenyl]pyrazin-2-yl}benzenesulfonamide | HCID 57444254 | — |
| Product | HCID 11960560 | HCID 11960560 | 77% |
Reaction Steps
Following the general method as outlined in Example 1 (Method B), starting from N-{3-[4-(chloromethyl)phenyl]pyrazin-2-yl}-2-(chloro) benzenesulfonamide (Intermediate 8), and 2,4-difluoro-N-methylaniline, the title compound was isolated as a yellow solid in 77% yield (92% purity by HPLC).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08796280B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-be760efe65ab47e29f947cf1498a64d3 |
| Source note | uspto-grants-2014_08 |