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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2401076Generated: November 1, 2026

2-Methylindole → HCID 57586067, compound

https://huagongshe.com/reaction/2401076

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-MethylindoleHCID 7224—
Reactant2-chloro-N-{3-[4-(chloromethyl)phenyl]pyrazin-2-yl}benzenesulfonamideHCID 57444254—
ProductHCID 57586067HCID 5758606781%

Reaction Steps

Following the general method as outlined in Example 1 (Method B), starting from 2-chloro-N-{3-[4-(chloromethyl)phenyl]pyrazin-2-yl}benzenesulfonamide (Intermediate 8), and 2-methyl-1-H-indole, the title compound was isolated as a yellow solid in 81% yield (96% purity by HPLC).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08796280B2
Source datasetuspto-grants-2014_08
ORD IDord-b3c7a7873c1348129c3c4607aa09fa1a
Source noteuspto-grants-2014_08