HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(2-Oxoethyl)-piperidine-1,4-dicarboxylic acid 1-tert-butyl ester 4-ethyl ester → HCID 71280635, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(2-Oxoethyl)-piperidine-1,4-dicarboxylic acid 1-tert-butyl ester 4-ethyl ester | HCID 58478423 | — |
| Reactant | 2-methyl-6-[(3R)-3-[(2S)-2-methylpyrrolidin-1-yl]pyrrolidin-1-yl]pyridin-3-amine | HCID 67480461 | — |
| Product | HCID 71280635 | HCID 71280635 | — |
Reaction Steps
The title compound was synthesized in essentially the same manner using the procedures as set forth in Step 1 of Example 1, by condensing 4-(2-oxo-ethyl)-piperidine-1,4-dicarboxylic acid 1-tert-butyl ester 4-ethyl ester (66 mg, 0.22 mmol) and 2-methyl-6-((2S,3′R)-2-methyl-[1,3′]bipyrrolidinyl-1′-yl)-pyridin-3-ylamine to obtain 111 mg of a crude solid, which was used without purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08796278B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-b5127db94488494a8af9cc470e7325dd |
| Source note | uspto-grants-2014_08 |