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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2401121Generated: October 30, 2026

4-(2-Oxoethyl)-piperidine-1,4-dicarboxylic acid 1-tert-butyl ester 4-ethyl ester → HCID 71280635, compound

https://huagongshe.com/reaction/2401121

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(2-Oxoethyl)-piperidine-1,4-dicarboxylic acid 1-tert-butyl ester 4-ethyl esterHCID 58478423—
Reactant2-methyl-6-[(3R)-3-[(2S)-2-methylpyrrolidin-1-yl]pyrrolidin-1-yl]pyridin-3-amineHCID 67480461—
ProductHCID 71280635HCID 71280635—

Reaction Steps

The title compound was synthesized in essentially the same manner using the procedures as set forth in Step 1 of Example 1, by condensing 4-(2-oxo-ethyl)-piperidine-1,4-dicarboxylic acid 1-tert-butyl ester 4-ethyl ester (66 mg, 0.22 mmol) and 2-methyl-6-((2S,3′R)-2-methyl-[1,3′]bipyrrolidinyl-1′-yl)-pyridin-3-ylamine to obtain 111 mg of a crude solid, which was used without purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08796278B2
Source datasetuspto-grants-2014_08
ORD IDord-b5127db94488494a8af9cc470e7325dd
Source noteuspto-grants-2014_08