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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2401133Generated: October 31, 2026

Hydrochloric Acid → HCID 54591075, compound

https://huagongshe.com/reaction/2401133

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 54590988HCID 54590988—
SolventEthanolHCID 702—
SolventMethanolHCID 887—
ProductHCID 54591075HCID 54591075100%

Reaction Steps

To a solution of 2-[2-methyl-6-((2S,3′R)-2-methyl-[1,3′]bipyrrolidinyl-1′-yl)-pyridin-3-yl]-1-oxo-2,9-diaza-spiro[5.5]undecane-9-carboxylic acid tert-butyl ester (20 mg, 0.04 mmol) in methanol (2 mL) was added a saturated solution of HCl in EtOH (2 mL) and stirred the resulting mixture for 20 hours. Concentrated the reaction mixture and dried under high vacuum to afford 20 mg (100% yield) of the title compound as a solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08796278B2
Source datasetuspto-grants-2014_08
ORD IDord-16177403f3884c42ae83ed4ddd88a6b0
Source noteuspto-grants-2014_08