HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Hydroxide → HCID 11254763, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | NBD-Cl | HCID 25043 | — |
| Reactant | Potassium Phosphate, Tribasic | HCID 62657 | — |
| Reactant | 4-Mercaptophenol | HCID 240147 | — |
| Reactant | Propanoic acid, 3-bromo-2-oxo-, ion(1-) | HCID 6994776 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 11254763 | HCID 11254763 | — |
Reaction Steps
A mixed solution of 4-chloro-7-nitro-2,1,3-benzoxadiazole (1 mmole) and 4-mercaptophenol (Sigma-Aldrich, Fine Chemicals) (2 mmoles) was made to react in 20 ml of ethanol: 1:1 potassium phosphate buffer, at pH 7.0 for 6 hours in a closed beaker, at 25° C. The pH was kept neutral by adding small quantities of KOH. At the end of the reaction, the excess 4-mercaptophenol was made to react with 1.5 mmoles of 3-bromopyruvate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08796317B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-779e70cf1aa34e2fbd05992db463de39 |
| Source note | uspto-grants-2014_08 |