HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 2774444, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Phthalic Anhydride | HCID 6811 | — |
| Reactant | 4-Fluorobenzylamine | HCID 67326 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 2774444 | HCID 2774444 | — |
Reaction Steps
4-Fluorobenzylamine (20 g, 160 mmol) in 10 mL CH2Cl2 was added to phthalic anhydride (5 g, 34 mmol) in 20 mL glacial acetic acid. The reaction was stirred at 100° C. for 4 h as water was collected with a Dean-Stark trap. Solvent was evaporated and the product was obtained by crystallization from ethanol (7.5 g, 87%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08796313B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-7f56e73cb6a147fa91692eaaa09cd62c |
| Source note | uspto-grants-2014_08 |