Ammonium Hydroxide → 6-aminopyridine-3-sulfonamide

Participants

Reaction Conditions

Reaction Steps

6-Chloropyridine-3-sulfonic acid amide (200 mg, 1 mmol) was placed in a sealed tube with 2 mL 28% aq. NH4OH and heated to 110° C. for 4 h. The mixture was diluted with brine and the title compound was collected as a solid (120 mg, 67%).

Provenance & Evidence