HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 178511697, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 1,5-Dichloro-6-fluoroisoquinoline | HCID 58468128 | — |
| Reactant | HCID 178418813 | HCID 178418813 | — |
| Reactant | HCID 178479273 | HCID 178479273 | — |
| Product | HCID 178511697 | HCID 178511697 | — |
Reaction Steps
Starting from cis-(4-hydroxy-cyclohexyl)-carbamic acid tert-butyl ester and 1,5-dichloro-6-fluoro-isoquinoline (9), the title compound was prepared as hydrochloride following the route described for 6-(cis-4-amino-cyclohexyloxy)-7-chloro-isoquinolin-1-ol hydrochloride (10). Rt=1.04 min (Method B). Detected mass: 293.1/295.1 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08796458B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-ef02469c4b5d4cb48ab014f214d70f1b |
| Source note | uspto-grants-2014_08 |