Trifluoroacetic acid → HCID 178510191, compound

HRID 2402736Notes

Reaction equation

HRID 2402736 reaction equation
[C:1]([C:3]1[C:16]2[N:15](C(OC(C)(C)C)=O)[C:14]3[C:9](=[CH:10][C:11]([N:24]4[CH2:29][CH2:28][O:27][CH2:26][CH2:25]4)=[CH:12][CH:13]=3)[S:8][C:7]=2[CH:6]=[C:5]([N:30]2[CH2:35][CH2:34][O:33][CH2:32][CH2:31]2)[CH:4]=1)#[N:2].[C:36]([OH:42])([C:38]([F:41])([F:40])[F:39])=[O:37]>ClCCl>[C:1]([C:3]1[C:16]2[C:7](=[S+:8][C:9]3[C:14]([N:15]=2)=[CH:13][CH:12]=[C:11]([N:24]2[CH2:25][CH2:26][O:27][CH2:28][CH2:29]2)[CH:10]=3)[CH:6]=[C:5]([N:30]2[CH2:35][CH2:34][O:33][CH2:32][CH2:31]2)[CH:4]=1)#[N:2].[F:39][C:38]([F:41])([F:40])[C:36]([O-:42])=[O:37]

Participants

4

Reactant 2

HCID 6422Trifluoroacetic acidHCID 90307516HCID 90307516, compound

Product 1

HCID 178510191HCID 178510191, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Dissolved tert-butyl 1-cyano-3,7-dimorpholino-10H-phenothiazine-10-carboxylate (63.0 mg, 0.0.127 mmol) in dichloromethane (3 mL). Added TFA (2 mL, 27 mmol). Stirred until the reaction was complete by TLC and LC/MS (2 h).

Workup

  1. customwas complete by TLC and LC/MS (2 h)

Sources & evidence

ORD record
ord-6d4afcc955be4a1d8ee29109d8af0fe9
Source dataset
uspto-grants-2014_08
Patent number
US08796448B1

Reaction notes

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