HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzaldehyde → Acetophenone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzaldehyde | HCID 240 | — |
| Reactant | Benzyl Alcohol | HCID 244 | — |
| Reactant | Oxygen | HCID 977 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Product | Acetophenone | HCID 7410 | — |
Reaction Steps
Expectedly, benzylic alcohols such as PhCH2OH, 4-CH3OPhCH2OH, 4-CF3PhCH2OH, and PhCHOHCH3 were also reactive (0.1 mmol substrate, 5 μmol Pd-POM-1, 1 ml TFT, 2 bar O2, and 110° C. for 20 minutes), all yielding the corresponding benzaldehyde derivatives or acetophenone with >95% yields with no observed by-products.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08796482B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-c0ce8cee54df4558ab33237bc87ef6b2 |
| Source note | uspto-grants-2014_08 |