HRID2402935

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID8471

Triethylamine

C6H15N

HCID181649

3H-1,2,3-Triazolo[4,5-b]pyridine, 3-hydroxy-

C5H4N4O

结构：CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F

HCID9886157

Methanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)

C10H15F6N6OP

HCID52987785

Methyl 3-amino-5-chlorobenzoate

C8H8ClNO2

结构：CC(C)(C)OC(=O)N[C@@H](CCC(=O)O)C(=O)OC(C)(C)C.Cl

HCID131731743

未命名化合物

PRODUCTS

生成物

结构：N[C@@H](CCC(=O)Nc1cc(Cl)cc(C(=O)O)c1)C(=O)O

HCID66614843

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID6344

Dichloromethane

CH2Cl2

PROCEDURE

实验过程

38 mg (0.1 mmol) of HATU, 14 mg (0.1 mmol) of HOAt, 30 mg (0.1 mmol) of Boc-Glu-OtBu hydrochloride, 0.014 mL (0.1 mmol) of triethylamine and 1 mL of dichloromethane were added to 30 mg (0.1 mmol) of methyl 5-chloro-3-aminobenzoate, and stirred at room temperature overnight.