Aspirin → HCID 69295493, compound

HRID 2403132Notes

Reaction equation

HRID 2403132 reaction equation
[Cl-].[CH2:2]([N+:12]([CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH3:24])([CH3:14])[CH3:13])[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH3:11].[C:25]([O:28][C:29]1[C:30](=[CH:34][CH:35]=[CH:36][CH:37]=1)[C:31]([OH:33])=[O:32])(=[O:27])[CH3:26].[OH-].[Na+]>O>[C:25]([O:28][C:29]1[CH:37]=[CH:36][CH:35]=[CH:34][C:30]=1[C:31]([O-:33])=[O:32])(=[O:27])[CH3:26].[CH2:15]([N+:12]([CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH3:11])([CH3:14])[CH3:13])[CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH3:24]

Participants

5

Reactant 3

HCID 2244AspirinHCID 14798Sodium HydroxideHCID 23558Didecyldimethylammonium Chloride

Product 1

HCID 69295493HCID 69295493, compoundYield 90%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
60 °C

Procedure

A stoichiometric mixture of didecyldimethylammonium chloride, acetylsalicyclic acid, and NaOH in distilled water was stirred at 60° C. for 2 h and then cooled to room temperature. The aqueous solution was extracted by chloroform. Chloroform was removed and prepared didecyldimethylammonium 2-acetoxybenzoate with 90% yield was dried in vacuum.

Workup

  1. temperaturecooled to room temperature
  2. extractionThe aqueous solution was extracted by chloroform
  3. customChloroform was removed
  4. customprepared didecyldimethylammonium 2-acetoxybenzoate with 90% yield
  5. customwas dried in vacuum

Sources & evidence

ORD record
ord-934c959fd339492883d9988528f3b951
Source dataset
uspto-grants-2014_08
Patent number
US08802596B2

Reaction notes

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