Lithium hydroxide, monohydrate → Lithium 1-cyclohexylazetidine-2-carboxylate

HRID 2403165Notes

Reaction equation

HRID 2403165 reaction equation
[CH:1]1([N:7]2[CH2:10][CH2:9][CH:8]2[C:11]([O:13]C)=[O:12])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.O.[OH-].[Li+:17]>>[CH:1]1([N:7]2[CH2:10][CH2:9][CH:8]2[C:11]([O-:13])=[O:12])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[Li+:17]

Participants

3

Reactant 2

HCID 168937Lithium hydroxide, monohydrateHCID 3532286Methyl 1-cyclohexylazetidine-2-carboxylate

Product 1

HCID 86692757Lithium 1-cyclohexylazetidine-2-carboxylate

Procedure

The reaction of methyl 1-(cyclohexyl)azetidine-2-carboxylate 19A and lithium hydroxide monohydrate yielded lithium 1-(cyclohexyl)azetidine-2-carboxylate as a brown oil (quant). MS ISP (m/e): 184.2 (100) [(M+H)]+.

Sources & evidence

ORD record
ord-23aaea6d18eb492385b3381990d5707e
Source dataset
uspto-grants-2014_08
Patent number
US08802665B2

Reaction notes

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