HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lithium hydroxide, monohydrate → Lithium 1-(4,4-difluorocyclohexyl)azetidine-2-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lithium hydroxide, monohydrate | HCID 168937 | — |
| Reactant | Methyl 1-(4,4-difluorocyclohexyl)azetidine-2-carboxylate | HCID 86692750 | — |
| Product | Lithium 1-(4,4-difluorocyclohexyl)azetidine-2-carboxylate | HCID 86692758 | — |
Reaction Steps
The reaction of methyl 1-(4,4-difluorocyclohexyl)azetidine-2-carboxylate 19B and lithium hydroxide monohydrate yielded lithium 1-(4,4-difluorocyclohexyl)azetidine-2-carboxylate as a light yellow solid (quant). MS ISP (m/e): 220.2 (100) [(M+H)]+, 200.2 (100) [(M−HF+H)]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08802665B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-4b38f3ee749242ceb40458a645c6b140 |
| Source note | uspto-grants-2014_08 |