Lithium hydroxide, monohydrate → Lithium 1-(4,4-dimethylcyclohexyl)azetidine-2-carboxylate

HRID 2403167Notes

Reaction equation

HRID 2403167 reaction equation
[CH3:1][C:2]1([CH3:16])[CH2:7][CH2:6][CH:5]([N:8]2[CH2:11][CH2:10][CH:9]2[C:12]([O:14]C)=[O:13])[CH2:4][CH2:3]1.O.[OH-].[Li+:19]>>[CH3:1][C:2]1([CH3:16])[CH2:7][CH2:6][CH:5]([N:8]2[CH2:11][CH2:10][CH:9]2[C:12]([O-:14])=[O:13])[CH2:4][CH2:3]1.[Li+:19]

Participants

3

Reactant 2

HCID 168937Lithium hydroxide, monohydrateHCID 86692751Methyl 1-(4,4-dimethylcyclohexyl)azetidine-2-carboxylate

Product 1

HCID 86692760Lithium 1-(4,4-dimethylcyclohexyl)azetidine-2-carboxylate

Procedure

The reaction of methyl 1-(4,4-dimethylcyclohexyl)azetidine-2-carboxylate 19C and lithium hydroxide monohydrate yielded lithium 1-(4,4-dimethylcyclohexyl)azetidine-2-carboxylate as a light yellow solid (quant). MS ISP (m/e): 212.2 (100) [(M+H)]+.

Sources & evidence

ORD record
ord-2a0be35a6e9243f0a15c6b9cd5cd9858
Source dataset
uspto-grants-2014_08
Patent number
US08802665B2

Reaction notes

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