Lithium hydroxide, monohydrate → HCID 86692771, compound

HRID 2403169Notes

Reaction equation

HRID 2403169 reaction equation
[CH3:1][C:2]1([CH3:16])[CH2:7][CH:6]([N:8]2[CH2:11][CH2:10][CH:9]2[C:12]([O:14]C)=[O:13])[CH2:5][CH2:4][O:3]1.O.[OH-].[Li+:19]>>[CH3:1][C:2]1([CH3:16])[CH2:7][CH:6]([N:8]2[CH2:11][CH2:10][CH:9]2[C:12]([O-:14])=[O:13])[CH2:5][CH2:4][O:3]1.[Li+:19]

Participants

3

Reactant 2

HCID 168937Lithium hydroxide, monohydrateHCID 86692754HCID 86692754, compound

Product 1

HCID 86692771HCID 86692771, compoundYield 72%

Procedure

The reaction of methyl 1-(2,2-dimethyltetrahydro-2H-pyran-4-yl)azetidine-2-carboxylate 19H and lithium hydroxide monohydrate yielded lithium 1-(2,2-dimethyltetrahydro-2H-pyran-4-yl)azetidine-2-carboxylate as an off-white solid (72%). MS ISP (m/e): 212.1 (100) [(M+H)]+.

Sources & evidence

ORD record
ord-65137d3932a443ee839b35eb68ddb428
Source dataset
uspto-grants-2014_08
Patent number
US08802665B2

Reaction notes

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