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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2403170Generated: October 30, 2026

Lithium hydroxide, monohydrate → Lithium 1-(1-(ethoxycarbonyl)piperidin-4-yl)azetidine-2-carboxylate

https://huagongshe.com/reaction/2403170

Reaction equation

Participants

RoleNameHCIDCharge
ReactantLithium hydroxide, monohydrateHCID 168937—
ReactantEthyl 4-(2-(methoxycarbonyl)azetidin-1-yl)piperidine-1-carboxylateHCID 86692756—
ProductLithium 1-(1-(ethoxycarbonyl)piperidin-4-yl)azetidine-2-carboxylateHCID 86692776—

Reaction Steps

The reaction of ethyl 4-(2-(methoxycarbonyl)azetidin-1-yl)piperidine-1-carboxylate 19K and lithium hydroxide monohydrate yielded lithium 1-(1-(ethoxycarbonyl)piperidin-4-yl)azetidine-2-carboxylate as light yellow solid (quant.). MS ISP (m/e): 257.1 (100) [(M+H)]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08802665B2
Source datasetuspto-grants-2014_08
ORD IDord-73493803dfed4651a55bf3357d170723
Source noteuspto-grants-2014_08