Hydrochloric Acid → 1057385-15-5

HRID 2403384Notes

Reaction equation

HRID 2403384 reaction equation
C(OC([N:8]1[CH2:13][CH2:12][CH:11]([S:14]([N:17]2[CH2:22][CH2:21][O:20][CH2:19][CH2:18]2)(=[O:16])=[O:15])[CH2:10][CH2:9]1)=O)(C)(C)C.[ClH:23]>ClCCl.CO.CCOCC>[ClH:23].[NH:8]1[CH2:13][CH2:12][CH:11]([S:14]([N:17]2[CH2:22][CH2:21][O:20][CH2:19][CH2:18]2)(=[O:16])=[O:15])[CH2:10][CH2:9]1

Participants

6

Reactant 2

HCID 313Hydrochloric AcidHCID 66617699HCID 66617699, compound

Product 1

HCID 666176751057385-15-5

Reagents, catalysts & solvents 3

HCID 887MethanolSolventHCID 3283Diethyl EtherSolventHCID 6344DichloromethaneSolvent

Procedure

To a solution of 4-(morpholine-4-sulfonyl)-piperidine-1-carboxylic acid tert-butyl ester in dichloromethane (10 ml) and methanol (10 ml) was added 2M hydrogen chloride in ether (2 μL). The reaction mixture was stirred overnight. The solvents were removed in vacuo to yield 4-(piperidine-4-sulfonyl)-morpholine hydrochloride salt.

Workup

  1. customThe solvents were removed in vacuo

Sources & evidence

ORD record
ord-aa6cbc70345b43eba1e1680056828425
Source dataset
uspto-grants-2014_08
Patent number
US08802670B2

Reaction notes

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