HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 86619255, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 4-(6-(Bromomethyl)-2-chlorothieno[3,2-d]pyrimidin-4-yl)morpholine | HCID 46180726 | — |
| Reactant | HCID 66617827 | HCID 66617827 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 86619255 | HCID 86619255 | — |
Reaction Steps
Reaction between 6-(bromomethyl)-2-chloro-4-morpholinothieno[3,2-d]pyrimidine and (3S,5R)-1-methanesulfonyl-3,5-dimethyl-piperazine using potassium carbonate and acetonitrile yielded 2-chloro-6-((2S,6R)-4-methanesulfonyl-2,6-dimethyl-piperazin-1-ylmethyl)-4-morpholin-4-yl-thieno[3,2-d]pyrimidine. This compound was subjected to procedure A to yield the desired final compound which was purified using flash chromatography.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08802670B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-e963beca4b234c8592a31758bfbb7305 |
| Source note | uspto-grants-2014_08 |