Hydrochloric Acid → 956034-62-1

HRID 2403435Notes

Reaction equation

HRID 2403435 reaction equation
C(OC([N:8]1[CH2:13][CH2:12][CH:11]([CH2:14][N:15]2[CH:19]=[CH:18][CH:17]=[N:16]2)[CH2:10][CH2:9]1)=O)(C)(C)C.[ClH:20]>ClCCl.CCOCC>[ClH:20].[N:15]1([CH2:14][CH:11]2[CH2:10][CH2:9][NH:8][CH2:13][CH2:12]2)[CH:19]=[CH:18][CH:17]=[N:16]1

Participants

5

Reactant 2

HCID 313Hydrochloric AcidHCID 18538721HCID 18538721, compound

Product 1

HCID 66617726956034-62-1

Reagents, catalysts & solvents 2

HCID 3283Diethyl EtherSolventHCID 6344DichloromethaneSolvent

Procedure

To a solution of 4-Pyrazol-1-ylmethyl-piperidine-1-carboxylic acid tert-butyl ester (215 mg) in anhydrous dichloromethane (5 ml) was added 2M hydrogen chloride in ether (4.1 ml). The reaction mixture was stirred at room temperature for 6 hours. The solvents were removed in vacuo to yield 4-Pyrazol-1-ylmethyl-piperidine hydrochloride salt.

Workup

  1. customThe solvents were removed in vacuo

Sources & evidence

ORD record
ord-9496abf5cacd45cdbdd7b445045c784f
Source dataset
uspto-grants-2014_08
Patent number
US08802670B2

Reaction notes

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