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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2403439Generated: October 29, 2026

Hydrochloric Acid → 111247-63-3

https://huagongshe.com/reaction/2403439

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 53722296HCID 53722296—
SolventDiethyl EtherHCID 3283—
SolventDichloromethaneHCID 6344—
Product111247-63-3HCID 21241491—

Reaction Steps

To a solution of 4-(2-Oxo-pyrrolidin-1-ylmethyl)-piperidine-1-carboxylic acid tert-butyl ester in dichloromethane was added 2M hydrogen chloride in ether (1.78 ml). The reaction mixture was stirred at room temperature for 6 hours. The solvents were removed in vacuo to yield 1-Piperidin-4-ylmethyl-pyrrolidin-2-one hydrochloride salt.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08802670B2
Source datasetuspto-grants-2014_08
ORD IDord-156b1ededfa349bda72568b5da3877ca
Source noteuspto-grants-2014_08