HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-[6-(Methylamino)-2-pyridyl]ethan-1-ol → 3-[5-[2-(6-Methylamino-pyridin-2-yl)-ethoxy]-indol-1-yl}-hexanoic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-[6-(Methylamino)-2-pyridyl]ethan-1-ol | HCID 10534858 | — |
| Reactant | 3-(5-Hydroxy-indol-1-yl)-hexanoic acid ethyl ester | HCID 67426394 | — |
| Product | 3-[5-[2-(6-Methylamino-pyridin-2-yl)-ethoxy]-indol-1-yl}-hexanoic acid ethyl ester | HCID 67427718 | 25% |
Reaction Steps
The title compound was synthesized from 2-(6-methylamino-pyridin-2-yl)-ethanol and 3-(5-hydroxy-indol-1-yl)-hexanoic acid ethyl ester using the procedure described in Example 14, step (c), in 25% yield. The crude product was used in the next step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06855722B2 |
| Source dataset | uspto-grants-2005_02 |
| ORD ID | ord-e66a215461ab494fb55a2366a55c4ba4 |
| Source note | uspto-grants-2005_02 |