Iodoethane → 2-(Butyloxy)-9-{6-[1-(1-methylethyl)-4-piperidinyl]hexyl}-8-(methyloxy)-9H-purin-6-amine

HRID 2403876Notes

Reaction equation

HRID 2403876 reaction equation
C(N1CC[CH2:6][CH:5](CCN2C(OC)=NC3C2=NC(O[C@@H](C)CCC)=NC=3N)[CH2:4]1)C.[CH2:29]([O:33][C:34]1[N:42]=[C:41]2[C:37]([N:38]=[C:39]([O:55][CH3:56])[N:40]2[CH2:43][CH2:44][CH2:45][CH2:46][CH2:47][CH2:48][CH:49]2[CH2:54][CH2:53][NH:52][CH2:51][CH2:50]2)=[C:36]([NH2:57])[N:35]=1)[CH2:30][CH2:31][CH3:32].ICC>>[CH2:29]([O:33][C:34]1[N:42]=[C:41]2[C:37]([N:38]=[C:39]([O:55][CH3:56])[N:40]2[CH2:43][CH2:44][CH2:45][CH2:46][CH2:47][CH2:48][CH:49]2[CH2:50][CH2:51][N:52]([CH:5]([CH3:6])[CH3:4])[CH2:53][CH2:54]2)=[C:36]([NH2:57])[N:35]=1)[CH2:30][CH2:31][CH3:32]

Participants

4

Procedure

Prepared similarly to Intermediate 46 from 2-(butyloxy)-8-(methyloxy)-9-[6-(4-piperidinyl)hexyl]-9H-purin-6-amine and 2-iodoethane.

Sources & evidence

ORD record
ord-6aaaa5c71f394ad2a1a7fe84eeb3cfd1
Source dataset
uspto-grants-2014_08
Patent number
US08802684B2

Reaction notes

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