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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2403905Generated: November 1, 2026

1-Iodopropane → 6-Amino-2-(butyloxy)-9-[2-(1-propyl-3-piperidinyl)ethyl]-7,9-dihydro-8H-purin-8-one

https://huagongshe.com/reaction/2403905

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-IodopropaneHCID 33643—
Reactant2-(Butyloxy)-8-(methyloxy)-9-[2-(3-piperidinyl)ethyl]-9H-purin-6-amineHCID 58306262—
Product6-Amino-2-(butyloxy)-9-[2-(1-propyl-3-piperidinyl)ethyl]-7,9-dihydro-8H-purin-8-oneHCID 67180172—

Reaction Steps

Prepared similarly to Example 14 from 2-(butyloxy)-8-(methyloxy)-9-[2-(3-piperidinyl)ethyl]-9H-purin-6-amine and 1-iodopropane. LCMS (System A): tRET=0.69 min; MH+ 377

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08802684B2
Source datasetuspto-grants-2014_08
ORD IDord-95a7ee885be040c6b1c4259df3c0a870
Source noteuspto-grants-2014_08