Barium permanganate → HCID 44427556, compound

HRID 2404413Notes

Reaction equation

HRID 2404413 reaction equation
[S:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N:3]=[C:2]1[CH:10]([C:12]1[CH:17]=[CH:16][CH:15]=[C:14]([O:18][CH2:19][CH2:20][CH3:21])[CH:13]=1)[OH:11].[Mn]([O-])(=O)(=O)=O.[Ba+2].[Mn]([O-])(=O)(=O)=O>C(#N)C>[S:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N:3]=[C:2]1[C:10]([C:12]1[CH:17]=[CH:16][CH:15]=[C:14]([O:18][CH2:19][CH2:20][CH3:21])[CH:13]=1)=[O:11]

Participants

4

Reactant 2

HCID 24587Barium permanganateHCID 66835939HCID 66835939, compound

Product 1

HCID 44427556HCID 44427556, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

A mixture benzothiazol-2-yl(3-propoxyphenyl)methanol (1 g) and barium permanganate (0.95 g) in acetonitrile 15 mL) is refluxed for 30 minutes. The mixture is filtered over a clarcel pad, concentrated under reduced pressure and purified by column chromatography over silica gel (eluant heptane/ethyl acetate: 4/1) to give benzothiazol-2-yl(3-propoxyphenyl)methanone as a white cristalline solid.

Workup

  1. filtrationThe mixture is filtered over a clarcel pad
  2. concentrationconcentrated under reduced pressure
  3. custompurified by column chromatography over silica gel (eluant heptane/ethyl acetate: 4/1)

Sources & evidence

ORD record
ord-ba2397e138be4ebeb6363fbb8ee24ea5
Source dataset
uspto-grants-2014_08
Patent number
US08802664B2

Reaction notes

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