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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2404502Generated: November 1, 2026

2,6-Difluoro-N-[5-(3-trifluoromethyl-phenyl)-thiophen-2-yl]benzamide → 2,6-Difluoro-N-[5-(3-oxazol-5-yl-phenyl)-thiophen-2-yl]-benzamide

https://huagongshe.com/reaction/2404502

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,6-Difluoro-N-[5-(3-trifluoromethyl-phenyl)-thiophen-2-yl]benzamideHCID 58703377—
Reactant[3-(1,3-Oxazol-5-yl)phenyl]boronic acidHCID 69380386—
Product2,6-Difluoro-N-[5-(3-oxazol-5-yl-phenyl)-thiophen-2-yl]-benzamideHCID 58703376—

Reaction Steps

Compound 121 was synthesized in an analogous fashion as described for Compound 117 except that 3-(oxazol-5-yl)-benzeneboronic acid was used instead of 3-trifluoromethylbenzeneboronic acid in the final step.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08802721B2
Source datasetuspto-grants-2014_08
ORD IDord-8d018db0b453465dbeeab49e72b9f35e
Source noteuspto-grants-2014_08