Hydrochloric Acid → Lorcaserin hydrochloride

HRID 2404937Notes

Reaction equation

HRID 2404937 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[CH2:11][CH2:10][NH:9][CH2:8][C@H:7]([CH3:12])[C:6]=2[CH:13]=1.Cl>O>[ClH:1].[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[CH2:11][CH2:10][NH:9][CH2:8][C@H:7]([CH3:12])[C:6]=2[CH:13]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 11658860Lorcaserin

Product 1

HCID 11673085Lorcaserin hydrochloride

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

contacting the free base (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine with HCl in the presence of water to form (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride; and

Sources & evidence

ORD record
ord-b0ac81a9c4f84b18bb2f37b8c831ca70
Source dataset
uspto-grants-2014_08
Patent number
US08802845B2

Reaction notes

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