Formamide → HCID 178518064, compound

HRID 2404943Notes

Reaction equation

HRID 2404943 reaction equation
C([O:3][C:4]([C:6]1[C:7]2[CH2:15][CH2:14][CH2:13][CH2:12][C:8]=2[S:9][C:10]=1[NH2:11])=O)C.[CH:16]([NH2:18])=O>>[N:11]1[C:10]2[S:9][C:8]3[CH2:12][CH2:13][CH2:14][CH2:15][C:7]=3[C:6]=2[C:4]([OH:3])=[N:18][CH:16]=1

Participants

3

Reactant 2

HCID 713FormamideHCID 78262Ethyl 2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate

Product 1

HCID 178518064HCID 178518064, compound

Procedure

A solution of 10 millimol IV in 15 milliliter formamide was stirred at 100° C. for 3 hours then cooled down to room temperature. The reaction mixture was poured onto crushed ice with continuous stirring then collected by filtration. The product was washed with water and n-hexane, then dried.

Workup

  1. additionThe reaction mixture was poured
  2. customonto crushed ice
  3. filtrationthen collected by filtration
  4. washThe product was washed with water and n-hexane
  5. customdried

Sources & evidence

ORD record
ord-f0bb1876f5634d4286cc669c9e7cfd02
Source dataset
uspto-grants-2014_08
Patent number
US08802849B2

Reaction notes

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