HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 776593, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Cyclopropanecarbonyl chloride | HCID 77637 | — |
| Reactant | Ethyl 2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate | HCID 78262 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | HCID 776593 | HCID 776593 | — |
Reaction Steps
11 millimol cyclopropanecarbonyl chloride was added dropwise to the solution of 10 millimol IV in 25 milliliter pyridine at 5° C. The reaction mixture was stirred at this temperature for 1 hour, poured onto icecold 1N aqueous HCl, the precipitated solid was filtered off, washed with water and n-hexane, then dried.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08802849B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-b298b8a145d54ecc8e23550490f3cb51 |
| Source note | uspto-grants-2014_08 |