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HRID240497

反应详情

EQUATION

反应方程式

HRID 240497 的结构方程式

REACTANTS

反应物

3
结构：CCN(C(C)C)C(C)C
HCID81531

Diisopropylethylamine

C8H19N

结构：CC(C)(C)OC(=O)N1C[C@H]2CNC[C@H]2C1
HCID1514452

tert-Butyl (3aR,6aS)-hexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylate

C11H20N2O2

结构：Cc1cccc(C(=O)Nc2cncc(Cl)n2)c1
HCID86635811

未命名化合物

PRODUCTS

生成物

1
结构：Cc1cccc(C(=O)Nc2cncc(N3C[C@H]4CN(C(=O)OC(C)(C)C)C[C@H]4C3)n2)c1
HCID67265310

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CS(C)=O
溶剂HCID679

Dimethyl sulfoxide

C2H6OS

CONDITIONS

反应条件

温度
110 °C

PROCEDURE

实验过程

The product from Example 24A (130.5 mg, 0.53 mmol) was reacted with the product from Example 1C (149.6 mg, 0.70 mmol) and N,N-diisopropylethylamine (110 μL) in DMSO as described in Example 19A, except that the mixture was heated to 110° C. overnight, to afford the title compound. MS (DCI/NH3) m/z 424 (M+H)+.