Lawesson's reagent → HCID 86635813, compound

Participants

Reaction Conditions

Reaction Steps

The product from Example 42A (60 mg, 0.14 mmol) and Lawesson's reagent (27 mg, 0.068 mmol) were combined with toluene (3 mL) and stirred at 110° C. for 18 h. After cooling to room temperature, the reaction mixture was concentrated under reduced pressure and purified by silica gel flash chromatography (EtOAc, Rf=0.35) to provide the title compound (60 mg, 97%). MS (APCI) m/z 387 (M+H)+.

Provenance & Evidence