1-Bromo-2-nitrobenzene → HCID 68897890, compound

HRID 2405455Notes

Reaction equation

HRID 2405455 reaction equation
Br[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[N+:8]([O-:10])=[O:9].C([O-])(=O)C.[Na+].[Br:16][C:17]1[CH:18]=[C:19]([CH:21]=[CH:22][CH:23]=1)[NH2:20]>C(OCC)(=O)C>[Br:16][C:17]1[CH:18]=[C:19]([NH:20][C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=2[N+:8]([O-:10])=[O:9])[CH:21]=[CH:22][CH:23]=1

Participants

5

Reactant 3

HCID 113411-Bromo-2-nitrobenzeneHCID 115623-BromoanilineHCID 517045Sodium Acetate

Product 1

HCID 68897890HCID 68897890, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

10 g (49.5 mmol) of 2-bromonitrobenzene, 13 g (163 mmol) of sodium acetate, and 10 g (59 mmol) of 3-bromoaniline were stirred at 180° C. for 8 hours in an argon atmosphere. After cooling the reaction solution to room temperature, the reaction solution was diluted with ethyl acetate, and filtered. After concentrating the filtrate, the residue was washed with methanol to obtain (3-bromophenyl)-(2-nitrophenyl)amine.

Workup

  1. filtrationfiltered
  2. concentrationAfter concentrating the filtrate
  3. washthe residue was washed with methanol

Sources & evidence

ORD record
ord-fe61c18381024d13a15bc14c25e45914
Source dataset
uspto-grants-2014_08
Patent number
US08803420B2

Reaction notes

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