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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 240551Generated: October 29, 2026

Tert-butyl 4-(benzyloxy)pyridin-2-ylcarbamate → HCID 178452896, compound

https://huagongshe.com/reaction/240551

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTert-butyl 4-(benzyloxy)pyridin-2-ylcarbamateHCID 66937350—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductHCID 178452896HCID 178452896100%

Reaction Steps

To a solution of tert-butyl 4-(benzyloxy)pyridin-2-ylcarbamate (5.89 g, 19.6 mmol) in methanol was added palladium on carbon (1.04 g, 0.981 mmol). After stirring under a hydrogen balloon at room temperature for 70 minutes, the solids were removed by filtration. The filtrate was concentrated under reduced pressure and solidified under high vacuum to provide the product (4.12 g, 99%) as white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08648087B2
Source datasetuspto-grants-2014_02
ORD IDord-f8e0b6e7abb3461aa7b5e1fed25787b0
Source noteuspto-grants-2014_02