HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tert-butyl 4-(benzyloxy)pyridin-2-ylcarbamate → HCID 178452896, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tert-butyl 4-(benzyloxy)pyridin-2-ylcarbamate | HCID 66937350 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 178452896 | HCID 178452896 | 100% |
Reaction Steps
To a solution of tert-butyl 4-(benzyloxy)pyridin-2-ylcarbamate (5.89 g, 19.6 mmol) in methanol was added palladium on carbon (1.04 g, 0.981 mmol). After stirring under a hydrogen balloon at room temperature for 70 minutes, the solids were removed by filtration. The filtrate was concentrated under reduced pressure and solidified under high vacuum to provide the product (4.12 g, 99%) as white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08648087B2 |
| Source dataset | uspto-grants-2014_02 |
| ORD ID | ord-f8e0b6e7abb3461aa7b5e1fed25787b0 |
| Source note | uspto-grants-2014_02 |