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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 240554Generated: October 26, 2026

Dimethylformamide dimethyl acetal → HCID 178428760, compound

https://huagongshe.com/reaction/240554

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamide dimethyl acetalHCID 78373—
Reactant4-(2-Methyl-4-nitrophenoxy)pyridin-2-amineHCID 23153065—
SolventEthanolHCID 702—
ProductHCID 178428760HCID 178428760—

Reaction Conditions

Temperature80 °C

Reaction Steps

To a solution of 4-(2-methyl-4-nitrophenoxy)pyridin-2-amine (2.05 g, 8.34 mmol) in ethanol (9 mL) was added dimethoxy-N,N-dimethylmethanamine (1.18 mL, 8.34 mmol). After heating to 80° C. for 1 hour, the mixture was concentrated under reduced pressure to provide the crude product as dark oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08648087B2
Source datasetuspto-grants-2014_02
ORD IDord-10476781d2334df78bb477caee31f24e
Source noteuspto-grants-2014_02