4-Bromobenzaldehyde → HCID 68543749, compound

HRID 2405546Notes

Reaction equation

HRID 2405546 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8](=[O:22])[CH2:9][S:10]([CH2:13][C:14]2[CH:19]=[CH:18][C:17]([O:20][CH3:21])=[CH:16][CH:15]=2)(=[O:12])=[O:11])=[CH:4][CH:3]=1.[Br:23][C:24]1[CH:31]=[CH:30][C:27]([CH:28]=O)=[CH:26][CH:25]=1>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([C:8](=[O:22])/[C:9](/[S:10]([CH2:13][C:14]2[CH:15]=[CH:16][C:17]([O:20][CH3:21])=[CH:18][CH:19]=2)(=[O:11])=[O:12])=[CH:28]\[C:27]2[CH:30]=[CH:31][C:24]([Br:23])=[CH:25][CH:26]=2)=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 707414-BromobenzaldehydeHCID 68539594HCID 68539594, compound

Product 1

HCID 68543749HCID 68543749, compound

Procedure

The title compound is prepared by the methods described in Synthesis Example 10. A solution of 1-(4-bromophenyl)-2-(4-methoxybenzylsulfonyl)ethanone (10 mmol) and 4-bromobenzaldehyde (10 mmol) was subjected to the procedure described as Method A in part C of Synthesis Example 10 and the product obtained was purified by column chromatography. m.p. 146-150° C.

Workup

  1. customdescribed in Synthesis Example 10
  2. customdescribed as Method A in part C of Synthesis Example 10
  3. customthe product obtained
  4. customwas purified by column chromatography

Sources & evidence

ORD record
ord-042243b2e9334b2baafef90410ad9a08
Source dataset
uspto-grants-2014_08
Patent number
US08808702B2

Reaction notes

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