4-Bromobenzaldehyde → HCID 68540279, compound

HRID 2405548Notes

Reaction equation

HRID 2405548 reaction equation
[I:1][C:2]1[CH:7]=[CH:6][C:5]([C:8](=O)[CH2:9][S:10]([CH2:13][C:14]2[CH:19]=[CH:18][C:17]([I:20])=[CH:16][CH:15]=2)(=[O:12])=[O:11])=[CH:4][CH:3]=1.[Br:22][C:23]1[CH:30]=[CH:29][C:26]([CH:27]=[O:28])=[CH:25][CH:24]=1>>[Br:22][C:23]1[CH:30]=[CH:29][C:26]([C:27](=[O:28])/[C:9](/[S:10]([CH2:13][C:14]2[CH:19]=[CH:18][C:17]([I:20])=[CH:16][CH:15]=2)(=[O:12])=[O:11])=[CH:8]\[C:5]2[CH:4]=[CH:3][C:2]([I:1])=[CH:7][CH:6]=2)=[CH:25][CH:24]=1

Participants

3

Reactant 2

HCID 707414-BromobenzaldehydeHCID 68543718HCID 68543718, compound

Product 1

HCID 68540279HCID 68540279, compound

Procedure

The title compound is prepared by the methods described in Synthesis Example 10. A solution of 1-(4-iodophenyl)-2-(4-iodobenzylsulfonyl)ethanone (10 mmol) and 4-bromobenzaldehyde (10 mmol) was subjected to the procedure described as Method A in part C of Synthesis Example 10 and the product obtained was purified by column chromatography.

Workup

  1. customdescribed in Synthesis Example 10
  2. customdescribed as Method A in part C of Synthesis Example 10
  3. customthe product obtained
  4. customwas purified by column chromatography

Sources & evidence

ORD record
ord-0822430366b8433e95cce8791a856315
Source dataset
uspto-grants-2014_08
Patent number
US08808702B2

Reaction notes

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