反应详情

tert-butyldimethyl((4-(prop-1-yn-1-yl)benzyl)oxy)silane (252 mg, 0.968 mmol) was dissolved in 20 mL of ethyl acetate, and then passed through H-Cube apparatus equipped with 10% Pd/C catridge under 20 bar of hydrogen pressure at a speed of 0.5 mL/min. The solution thus passed was concentrated by distillation under reduced pressure to obtain 251 mg (0.949 mmol, 98%) of the desired compound.

1. concentrationThe solution thus passed was concentrated by distillation under reduced pressure