Diisopropylethylamine → HCID 178431648, compound

Participants

Reaction Steps

DIPEA (75 mg) and 3-bromo-1,1,1-trifluoropropane (500 mg) were added to a solution of 3a-[(R)-6,6-dimethyl-4,4-dioxo-5-(4-piperidin-4-yl-phenyl)-5,6-dihydro-4H-4lambda*6*-[1,4,3]oxathiazin-2-ylamino]hexahydro-2,5-methanopentalene-2-carboxamide (73 mg) in DMF (1.5 mL), and the mixture was stirred overnight. The resulting mixture was purified in a purification laboratory by means of preparative HPLC. This gave the product with a molecular weight of 596.7 g/mol (C29H39F3N4O4S); MS (ESI): m/e=597 (M+H+).

Provenance & Evidence