Phenylsulfamate → Sulfamic acid 1-trifluoroethyl-cyclopropyl ester

HRID 2405795ノート

反応式

HRID 2405795 の反応式
C1([O:7][S:8](=O)(=[O:10])[NH2:9])C=CC=CC=1.[F:12][C:13]([F:20])([F:19])[CH2:14][C:15]1([OH:18])[CH2:17][CH2:16]1>>[F:12][C:13]([F:20])([F:19])[CH2:14][C:15]1([O:18][S:8](=[O:10])(=[O:7])[NH2:9])[CH2:17][CH2:16]1

参加物

3

反応物 2

HCID 11030308PhenylsulfamateHCID 574451531-(2,2,2-Trifluoroethyl)cyclopropan-1-ol

生成物 1

HCID 57785491Sulfamic acid 1-trifluoroethyl-cyclopropyl ester

実験手順

Sulfamic acid 1-trifluoroethyl-cyclopropyl ester was synthesized according to the method presented in the synthesis of sulfamic acid phenyl ester in Example 1 with the exception of utilizing 1-trifluoroethylcyclopropanol (synthesized by methods reported in Synthesis 1991, 234) to obtain sulfamic acid 1-trifluoroethyl-cyclopropyl ester.

後処理

  1. customSulfamic acid 1-trifluoroethyl-cyclopropyl ester was synthesized

出典と根拠

ORDレコード
ord-4d5f66587ce143d88f1a0a56ddffc01f
出典データセット
uspto-grants-2014_08
特許番号
US08809267B2

反応ノート

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