2-Amino-2-cyclopropylacetic acid → HCID 68616869, compound

Participants

Reaction Steps

Cyclopropyl-[(tetrahydro-furan-3-yloxycarbonylamino)]-acetic acid was prepared according to the method presented in the synthesis of the intermediate 3,3-dimethyl-2-(tetrahydro-furan-3-yloxycarbonylamino)-butyric acid in Example 62. Treatment of amino-cyclopropyl-acetic acid with carbonic acid 4-nitro-phenyl ester tetrahydro-furan-3-yl ester occurred under the same conditions, adjusted for scale, to provide the desired cyclopropyl-[(tetrahydro-furan-3-yloxycarbonylamino)]-acetic acid.

Provenance & Evidence