HuagongsheHuagongshe Chemistry Print Report · For research reference only
7-(Benzyloxy)-[1,2,4]triazolo[1,5-a]pyridine → HCID 178516352, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 7-(Benzyloxy)-[1,2,4]triazolo[1,5-a]pyridine | HCID 66937106 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 178516352 | HCID 178516352 | — |
Reaction Steps
A 250 mL, single-neck, round-bottomed flask was charged with 7-(benzyloxy)-[1,2,4]triazolo[1,5-a]pyridine (3.20 g, 14.2 mmol), Pd/C (0.756 g, 0.710 mmol), and THF (125 mL). The reaction was stirred under an atmosphere of hydrogen for 16 hours, then filtered (GF paper) and concentrated to a white solid. The solids were titrated with EtOAc and collected by filtration to provide the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08648087B2 |
| Source dataset | uspto-grants-2014_02 |
| ORD ID | ord-8dc86bf5530f48a88256ee9f41785e31 |
| Source note | uspto-grants-2014_02 |