Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 240584Generated: October 31, 2026

7-(Benzyloxy)-[1,2,4]triazolo[1,5-a]pyridine → HCID 178516352, compound

https://huagongshe.com/reaction/240584

Reaction equation

Participants

RoleNameHCIDCharge
Reactant7-(Benzyloxy)-[1,2,4]triazolo[1,5-a]pyridineHCID 66937106—
CatalystPalladiumHCID 23938—
SolventTetrahydrofuranHCID 8028—
ProductHCID 178516352HCID 178516352—

Reaction Steps

A 250 mL, single-neck, round-bottomed flask was charged with 7-(benzyloxy)-[1,2,4]triazolo[1,5-a]pyridine (3.20 g, 14.2 mmol), Pd/C (0.756 g, 0.710 mmol), and THF (125 mL). The reaction was stirred under an atmosphere of hydrogen for 16 hours, then filtered (GF paper) and concentrated to a white solid. The solids were titrated with EtOAc and collected by filtration to provide the desired product.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08648087B2
Source datasetuspto-grants-2014_02
ORD IDord-8dc86bf5530f48a88256ee9f41785e31
Source noteuspto-grants-2014_02