反应详情

Amoniumformiate (0.238 g) was added into a suspension of (S)-2,2,2-trifluoro-1-(3-(5-methyl-2-nitrophenoxy)piperidin-1-yl)ethanone and palladium on charcoal (50.0 mg) in MeOH (6.0 ml) at room temperature. The mixture was heated at reflux for 40 mins. The mixture was filtered through a pad of celite and the filtercake was washed with dichloromethane. The filtrate was washed with water and. The residue was purfied by chromatography.

1. temperatureThe mixture was heated
2. temperatureat reflux for 40 mins
3. filtrationThe mixture was filtered through a pad of celite
4. washthe filtercake was washed with dichloromethane
5. washThe filtrate was washed with water